Nickan Research Institute Journal of Parathyroid Disease 2345-6558 10 1 2022 01 01 The therapeutic, preventive, and immune-boosting effects of some minerals and vitamins in COVID-19: A narrative review e9151 e9151 10.34172/jpd.2022.9151 EN Afagh Hassanzadeh Rad https://orcid.org/0000-0001-6980-8866 Amirhossein Fakhre Yaseri https://orcid.org/0000-0001-8893-9802 Journal Article 10.34172/jpd.2022.9151 2022 07 17 2022 08 22 Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which produces COVID-19, is the most deadly coronavirus ever identified. Essential treatments and nutrition are crucial for improving the immune system against viral infection. As studies recommended checking the nutritional state of COVID-19-infected individuals before treatment, we aimed to review the therapeutic, preventive, and immune-boosting effects of some minerals and vitamins on COVID-19. This review emphasizes the possible therapeutic, preventive, and immune-boosting effects of some minerals such as zinc, selenium, iron, calcium, phosphorus, potassium, and magnesium and vitamins C, D, and E on COVID-19 patients. Regarding the evidence that shows the preventive effects of vitamins and minerals on serious COVID-19, it seems that clinicians have to consider these factors precisely.