Nickan Research Institute Journal of Parathyroid Disease 2345-6558 4 2 2016 04 01 Serum 25-hydroxy vitamin D level in diabetic patients versus normal individuals; a pilot study 40 43 EN Marzieh Kafeshani Mahtab Zarafshani Sara Shokri-Moghaddam Ali Ahmadi Hamid Nasri Journal Article Introduction: Vitamin D deficiency is a common health problem throughout the world. There is growing interest in vitamin D status as a potentially adjustable risk factor for diabetes mellitus. Objectives: The main aim of this investigation is to assess, the possible differences of vitamin D serum value of diabetics versus normal persons. Patients and Methods: This study was a cross-sectional investigation was conducted on 106 persons (females; 44, males; 62) consisting of 75 subjects, were free of any diseases who had normal fasting blood sugar (FBS) and 31 type 2 diabetic patients. Blood level of 25-hydroxy vitamin D [25(OH) D] was FBS, 2-hour postprandial blood sugar (2-h PPBS), calcium, creatinine, and uric acid were measured using standard kits. The independent t test was used to determine the significance of any baseline differences between groups and Pearson correlation test was used to assess correlations by STATA software version 12. Results: The mean serum 25(OH) D concentration was 27.44± 3.66 and 27.64 ± 5.62 nmol/l in diabetics, and normal persons respectively. There was any significant difference in serum 25-hydroxy vitamin D level between diabetic and normal individuals. The prevalence of vitamin D deficiency (<50 nmol/l) was 88.87% in diabetic and 92% in normal subjects respectively. Conclusion: The prevalence of vitamin D deficiency was high in two groups, however, there was not any significant difference in serum 25-hydroxy vitamin D level between diabetics and normal individuals.