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J Parathyr Dis. 2014;2(1): 7-8.
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Epidemiology and Prevention

Primary hyperparathyroidism and kidney; recent findings

Azar Baradaran*

1 Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran.
*Corresponding Author: *Corresponding author: Dr. Azar Baradaran, , Email: azarbaradaran@med.mui.ac.ir

Implication for health policy/practice/research/medical education

The name primary hyperparathyroidism denotes to the improper overproduction of the parathyroid hormone conducting to abnormal calcium homeostasis. High levels of parathyroid hormone lead to increased synthesis of 1,25(OH)2D (which increases intestinal calcium absorption), increased kidney resorption of calcium, increased resorption of the bone and phosphaturia. The classical clinical manifestation of primary hyperparathyroidism is the ‘stone and bone’ disease. Kidney manifestations of primary hyperparathyroidism include nephrocalcinosis, hypercalciuria, nephrolithiasis, chronic kidney disease, and kidney tubular dysfunction.

Please cite this paper as: Baradaran A. Primary hyperparathyroidism and kidney; recent findings. J Parathyr Dis 2014; 2(1): 7-8.

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ePublished: 07 Feb 2014
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