Implication for health policy/practice/research/medical education
Increased parathormone can stimulate bone demineralization and lead to high-turnover bone disease; a situation marked by accelerated rates of bone absorption and reabsorption. This condition defined as secondary hyperparathyroidism and requires treatment. Various studies have shown the contradictory effect of vitamin C on parathormone secretion, however some of the investigations showed its beneficial property to lower serum parathormone level. Patients on hemodialysis are at risk for low levels of serum vitamin C too. Vitamin C is a water-soluble substance which can be reduced by routine hemodialysis. This subject, however needs further investigation with larger samples, to fully define the impact of vitamin C on parathormone secretion.
Please cite this paper as: Nasri H. Impact of vitamin C on parathormone secretion in patients on hemodialysis with secondary hyperparathyroidism. J Parathyr Dis 2013; 1(2):29-31.