The need for a reliable bone biomarker to better assess chronic kidney disease mineral and bone disorder

Abstract

Chronic kidney disease mineral and bone disorder is a metabolic bone disease present in almost all uremic patients. There are no good markers of bone resorption available for uremic patients. The validity of parathormone as a surrogate marker of bone and mineral disorders has been questioned over the past decade. We need to shift from Surrogate markers to bone markers.

Keywords: Chronic kidney disease, Mineral and bone disorder, Renal osteodystrophy, Parathyroid hormone, End- stage renal disease, Hypoparathyroidism