Elaheh Jahanian
1, Mansoor Karimifar
2, Mahmoud Rafieian-Kopaei
3*1 Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.
2 Department of Rheumatology, Isfahan University of Medical Sciences, Alzahra Hospital, Isfahan, Iran.
3 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Abstract
Bone is a dynamic organ undergoing remodeling through the coordinated resorption and formation activities between osteoblasts and osteoclasts. Osteoporosis is regarded as degenerative disease that is one of the biggest problems in elderly people. Osteoporosis is a multi-factorial disease. Age-related oxidative stress causes osteoporosis via adversely affecting both osteoblasts and osteoclasts. On the other hands, one of defense mechanisms against reactive oxygen species is antioxidant. Fruits and vegetables are the sources of antioxidants alleviating osteoporosis caused by oxidative stress. Hence, the aim of this review article is to illustrate the favored effects of antioxidants therapy to mitigate osteoporosis caused by oxidative stress.
Implication for health policy/practice/research/
medical education
Osteoporosis is regarded as degenerative disease that is one
of the biggest problems in elderly people. Osteoporosis is a
multi-factorial disease. Age-related oxidative stress causes
osteoporosis via adversely affecting both osteoblasts and
osteoclasts. On the other hands, one of defense mechanisms
against reactive oxygen species is antioxidant. Fruits and
vegetables are the sources of antioxidants alleviating
osteoporosis caused by oxidative stress.
Please cite this paper as: Jahanian E, Karimifar M, Rafieian-Kopaei M. Antioxidants as a novel way to alleviate the adverse effects of oxidative stress in osteoporosis. J Parathyr Dis. 2016;4(2):60-65.